Muhammad Haikal Algifari, Dedat Prismantoro, Anggita Rahmi Hafsari, Mia Miranti, Wan Abd Al Qadr Imad Wan-Mohtar, Abdullah Bilal Ozturk, Azwir Anhar, Zul Ilham, Ravindra Chandra Joshi, Febri Doni
The fungal genus Trichoderma is widely recognized for its diverse agricultural applications, particularly its ability to enhance plant growth, suppress pathogens, facilitate organic matter decomposition and nutrient cycling. Trichoderma-produced enzymes play a crucial role in these processes, making them valuable biocatalysts for sustainable crop production. However, despite their well-documented benefits, the full potential of these enzymes remains underexplored. A deeper understanding of the molecular mechanisms governing Trichoderma’s enzymatic activity in agricultural systems could provide critical insights into optimizing their efficacy. To this end, this review examines the current applications of Trichoderma-derived enzymes in sustainable agriculture, highlights the challenges associated with their industrial-scale use, and explores emerging technologies such as genetic engineering, enzyme engineering and design, and innovative enzyme production strategies. Addressing these challenges and leveraging advanced biotechnological tools will allow Trichoderma-produced enzymes to be further optimized for broader agricultural applications, contributing to sustainable food production and environmental conservation. © 2025 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Padjadjaran, West Java, Jatinangor, Indonesia; Doctorate Program in Biotechnology, Graduate School, Universitas Padjadjaran, West Java, Bandung, Indonesia; Functional Omics and Bioprocess Development Laboratory, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia; Department of Biology, Faculty of Science and Technology, Universitas Islam Negeri Sunan Gunung Djati Bandung, West Java, Bandung, Indonesia; Department of Chemical Engineering, Faculty of Chemical and Metallurgical Engineering, Yildiz Technical University, Eselner, Istanbul, Turkey; Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, West Sumatra, Padang, Indonesia; Biomass Energy Laboratory, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, Kuala Lumpur, Malaysia; Philippine Rice Research Institute, Maligaya, Science City of Muñoz, Ecija, Nueva, Philippines; Department of Global Development, Cornell University, Ithaca, NY, United States
