Oluwole Solomon Oladeji, Kehinde Abraham Odelade, Ahmed Mahal, Ahmad J. Obaidullah, Rahadian Zainul
Alkaloids are a complex class of biologically active compounds with a broad spectrum of health-related applications. Particularly the alkaloids of indole, steroidal, terpenoids, isoquinoline, and bisbenzylisoquinoline have been extensively investigated. Ultimately, substantial advancement has been highlighted in the investigation of chemical constituents and the therapeutic benefits of plant alkaloids, particularly during the last ten years. A total of 386 alkaloids have been isolated from over 40 families, including Apocynaceae, Annonaceae, Rubiaceae, Menispermaceae, Ranunculaceae, Buxaceae, Papaveraceae, Magnoliaceae, Rutaceae and Phyllanthaceae. This paper will investigate several alkaloids that have been isolated from botanical medicines as well as offer an in-depth analysis of their cytotoxic properties. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.
Natural Products Research Unit, Department of Physical Sciences, College of Pure and Applied Sciences, Landmark University, Omu-Aran, PMB 1001, Nigeria; Landmark University Sustainable Development Goals III (SDG 3), Good Health and Well-Being, Landmark University, Omu-Aran, PMB 1001, Nigeria; Department of Science Laboratory Technology, Federal Polytechnic, Ogbomoso, Ayede, Nigeria; Department of Medical Biochemical Analysis, College of Health Technology, Cihan University-Erbil, Kurdistan Region, Erbil, Iraq; Institut für Chemie, Universität Rostock, Albert-Einstein-Strasse 3a, Rostock, 18059, Germany; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, Padang, Indonesia; Center for Advanced Material Processing, Artificial Intelligence, and Biophysics Informatics (CAMBIOTICS), Universitas Negeri Padang, Padang, Indonesia
