Microwave Crosslinked Chitosan/Green Fluorescent Carbon Nanoparticles Film: Comprehensive Characterisation and Antimicrobial Performance

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Mas Syazlin Masbah, Anwar Iqbal, Junichi Ida, Rabiatul Basria S. M. N. Mydin, Nur Asshifa Md Noh, Rahadian Zainul, M. Hazwan Hussin

2024 Journal of Physical Science Vol. 35 Issue 2 Article Cited by 2 Quartile

Abstract

Conventional crosslinkers used to reduce the swelling of chitosan films are prone to toxicity. Fluorescent carbon nanoparticles, on the other hand, present a safer alternative. This study aims to crosslink microwave-synthesised green fluorescent carbon nanoparticles (GFCNPs) with high quantum yield (44%) and chitosan film via solvent casting (CHT/GFCNPs). The particle size distribution of GFCNPs predominantly ranged from 5 nm to 15 nm. X-ray diffraction (XRD) and high-resolution transmission electron microscopy (HRTEM) analyses indicated the presence of graphite. Attenuated total reflectance-fourier transform infrared (ATR-FTIR) spectroscopy detected various functional groups that enabled crosslinking. The CHT/GFCNPs exhibited significantly lower swelling (500%) compared to chitosan film (2300%). Preliminary findings of antibacterial activity demonstrated the effects of the compounds on bacteria with different cell wall structures, namely Gram-positive and Gram-negative bacteria. The CHT/ GFCNPs showed potential antibacterial activity against Staphylococcus aureus, a Grampositive bacteria, compared to Escherichia coli, a Gram-negative bacteria. © Penerbit Universiti Sains Malaysia, 2024. This work is licensed under the terms of the Creative Commons Attribution (CC BY) (http://creativecommons.org/licenses/by/4.0/).

Affiliations

School of Chemical Sciences, Universiti Sains Malaysia, USM, Pulau Pinang, 11800, Malaysia; Faculty of Science and Engineering, Soka University, 1-236 Tangi-machi, Tokyo, Hachioji, 192-8577, Japan; Department of Biomedical Science, Advanced Medical and Dental Institute, Universiti Sains Malaysia, Pulau Pinang, Kepala Batas, 13200, Malaysia; School of Biological Sciences, Universiti Sains Malaysia, USM, Pulau Pinang, 11800, Malaysia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, West Sumatra, Padang, Indonesia; Centre for Energy and Power Electronics Research, Universitas Negeri Padang, West Sumatra, Padang, Indonesia