Rollando Rollando, Christina Novratilova Hardi, Nur Aziz, Dodi Iskandar, Rahadian Zainul
In this study, acute toxicity tests and liver histopathology in male white rats were used to explore the immunomodulatory potential of MCH2 syrup, which was prepared with a 2:2 ratio of Phyllantus niruri L. and Morinda citrifolia L. The study, which used a posttest-only control group design, entailed giving different dosages of MCH2 syrup orally and then assessing behavioral changes, body weight changes, and liver histological characteristics like degeneration, congestion, and necrosis. The results validated the immunomodulatory activity of MCH2 syrup by showing notable effects on the liver histology of male white rats, demonstrating modest and quickly regenerating damage. © 2024 Rollando.
Pharmacy Department, Faculty of Health Sciences, Ma Chung University, Malang, 65151, Indonesia; Agricultural Technology Department, Polytechnic State Pontianak, Pontianak, 78115, Indonesia; Chemistry Department, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, Padang, 25131, Indonesia
