Muhammad Syahrur Ramadhan, Riga Riga, Euis Holisotan Hakim
An endophytic fungus identified as Aspergillus carbonarius was obtained from from sea sponge Aaptos suberitioides. Phytochemical study of fungal A. carbonarius led to the isolation of four compounds (1-4) of which compound 1 was a new isocoumarin derivative, (R)-6-hydroxy-3-(1-hydroxypropan-2-yl)-8-methoxyisocoumarin. The others (compounds 2-4) were the known compounds. Isolation of these compounds was performed using vacuum liquid dan column chromatography. The structure elucidation and identification of these compounds were conducted with the help of NMR and HR-ESI-MS spectroscopic data. All isolated compounds (1-4) were tested for their antibacterial activity against five bacterial strains and displayed inactive activity against all tested microorganisms. © (2023), (Slovak University of Agriculture). All Rights Reserved.
Natural Products Research Group, Organic Chemistry Division, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung, Jalan Ganesha 10, Bandung, 40116, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, Jalan Prof. Dr. Hamka, Padang, 25131, Indonesia
