The phytochemical and pharmacological activity of extract Kirinyuh (Chromolaena odorata L.) leaves: A Review

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Erna Harfiani, Yudhi Nugraha, Citra Ayu Aprilia, Feda Anisah Makkiyah, Ratna Puspita, Viol Dhea Kharisma, Muhammad Hermawan Widyananda, Ahmad Affan Ali Murtadlo, Dora Dayu Rahma Turista, Muhammad Badrut Tamam, Riso Sari Mandeli, Mirella Fonda Maahury, Devi Purnamasari, Muhammad Arya Ghifari, Muhammad Thoriq Albari, Muhammad Raffi Ghifari, Asmi Citra Malina A.R. Tasakka, Alexander Patera Nugraha, Rahadian Zainul

2022 Pharmacognosy Journal Vol. 14 Issue 5 Article Cited by 5 Quartile

Abstract

C. odorata L. is considered to be a plant weed that is scattered in various climates. As a weed, this plant contains a variety of beneficial secondary metabolites. Several studies have shown the benefits of C. odorata L. leaf extract. This study reviews the metabolite content and the pharmacological activities of C. odorata L. leaf extract. A literature search was carried out to obtain various studies related to the use of this plant extract. Secondary metabolites identified in C. odorata L. are alkaloids, flavonoids, tannins, saponins, and steroids. Several reports have also shown that even though it is considered a weed, C. odorata L. leaf extract also provides many benefits due to its pharmacological activities. Various pharmacological activities include anti-inflammatory, anti-microbial, antioxidant, antidyslipidemia, hematologic agent, anti-diabetic and anti-cataract, analgesic and antipyretic, wound healing, anti-malaria, mosquito larvicidal, anti-hypercholesterolemia, and antifungal. © 2022 Phcogj.Com.

Affiliations

Department ofPharmacology and Pharmacy, Medical Faculty, UPN Veteran Jakarta, Jakarta, Indonesia; Badan Riset dan Inovasi Nasional, Jakarta, Indonesia; Department of Surgery, Medical Faculty, UPN Veteran Jakarta, Jakarta, Indonesia; Department of Biochemistry, Medical Faculty, UPN Veteran Jakarta, Jakarta, Indonesia; Division of Molecular Biology and Genetics, Generasi Biologi Indonesia Foundation, Gresik, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, Malang, Indonesia; Biology Education Department, Faculty of Teacher Training and Education, Mulawarman University, Samarinda, Indonesia; Department of Biology, Faculty of Sciences and Technology, Universitas Muhammadiyah Lamongan, Lamongan, Indonesia; Environmental Science, Postgraduate Programme, Universitas Negeri Padang, Padang, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Pattimura, Ambon, Indonesia; Department of Radiology Engineering, Universitas Awal Bros, Pekanbaru, Indonesia; Department of Informatics Engineering, Faculty of Computer Sciences, Universitas Brawijaya, Malang, Indonesia; Faculty of Marine Science and Fisheries, Universitas Hasanuddin, Makassar, Indonesia; Department of Orthodontics, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia; Center for Advanced Material Processing, Artificial Intelligence, and Biophysic Informatics (CAMP-BIOTICS), Universitas Negeri Padang, Padang, Indonesia; Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, Padang, Indonesia