N. Gussarsi, A. Ulianas, B. Oktavia, S. Aini, T.L. Ling, S.A. Hanifah, R.A. Hassan
Molecularly Imprinted conducting polymers (MICP) from the monomer’s aniline and methacrylic acid have been successfully developed as uric acid absorbers. The method used to synthesize the MICP membrane in this study is based on photopolymerization by using ultraviolet (UV) light radiation. The electrical conductivity analysis of the resulting MICP membrane by using a four-point probe (FPP) revealed that the MICP membrane has an electrical conductivity of 1.9904 ohm-1 cm-1. FTIR characterization of the extracted MICP membrane did not find an N-H absorption peak, whilst the re-extracted MICP membrane exhibited an absorption peak in the wavenumber region of 910-665 cm-1, which corresponds to the N-H functional group of uric acid. This suggests that the as-prepared MICPs membrane is capable of absorbing uric acid in solution. The optimum absorption conditions of the transparent MICP membrane for uric acid are pH 7.5 by using a 0.003 g MICP membrane with an absorption capacity of 0.741 mg g-1, and a contact time of 24 h. The uric acid MICP membrane has been successfully tested to absorb uric acid molecules in human blood by using an easy-touch GU uric acid meter with an absorption capacity of 0.57 mg g-1 at normal blood pH. © 2022, Rasayan Journal of Chemistry, c/o Dr. Pratima Sharma. All rights reserved.
Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Negeri Padang, Sumatera Barat, Padang, 25131, Indonesia; Biosensor & Chemical Sensor Research center, Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Negeri Padang, Sumatera Barat, Padang, 25131, Indonesia; Southeast Asia Disaster Prevention Research Initiative (SEADPRI), Institute for Environment and Development (LESTARI), Universiti Kebangsaan Malaysia, UKM, Selangor, Bangi, 43600, Malaysia; Department of Chemical Sciences, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Selangor, Bangi, 43600, Malaysia; Department of Chemistry, Faculty of Science, Ibb University, P.O. Box, Ibb, 70270, Yemen
