Mohamad Hafiz Ahmad Tajudin, Mohamad Syahrizal Ahmad, Illyas Md Isa, Norhayati Hashim, Anwar Ul-Hamid, Mohamad Idris Saidin, Rahadian Zainul, Suyanta M. Si
An electrochemical chemical sensor for the determination of uric acid (UA) with high sensitivity and a wide working range was fabricated using the layered zinc hydroxide-sodium dodecyl sulphate-propoxur (LZH-SDS-PRO) nanocomposite, modified with multiwall carbon nanotubes (MWCNT). The introduction of LZH-SDS-PRO as a conducting matrix has enhanced the conductivity of MWCNT. The morphology of LZH-SDS-PRO/MWCNT was characterized by transmission electron microscopy (TEM) and scanning electron microscopy (SEM), while electrochemical behavior of UA and K3[Fe(CN)6] at LZH-SDS-PRO/MWCNT paste electrode was studied by square wave and cyclic voltammetry, respectively. Under the optimized experimental conditions, the electrode established linear plot for UA concentrations 7.0 mol L-1 to 0.7 mmol L-1 (R2 = 0.9920) and LOD was calculated to be 4.28 µmol L-1 (S/N = 3). The fabricated LZH-SDS-PRO/MWCNT electrode was successsfully applied to urine samples, exhibiting excellent stability and reproducibility, which made it worthwhile for analytical applications. © 2022 by the authors; licensee IAPC, Zagreb, Croatia.
Faculty of Applied Sciences, Universiti Teknologi MARA, Perak Branch, Tapah Campus, Tapah Road, Perak, 35400, Malaysia; Department of Chemistry, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, Perak, Tanjong Malim, 35900, Malaysia; Nanotechnology Research Centre, Faculty of Science and Mathematics, Universiti Pendidikan Sultan Idris, Perak, Tanjong Malim, 35900, Malaysia; Center for Engineering Research, Research Institute, King Fahd University of Petroleum & Minerals, Dhahran, 31261, Saudi Arabia; Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Negeri Padang, West Sumatera, 25171, Indonesia; Department of Chemistry Education, Faculty of Mathematics and Natural Science, Yogyakarta State University, Indonesia
