Suryelita Suryelita, Riga Riga, Sri Benti Etika, Mariam Ulfah, Muh Ade Artasasta
AIM: The purpose of this research is to evaluate the antibacterial activity of endophytic fungi derived from the flowers of Andrographis paniculata (Sambiloto). METHODS: The endophytic fungi were obtained following the dilution method with potato dextrose agar as media. Four isolates of fungi have been obtained and then fermented with rice media for 3 weeks. The fermented fungi were extracted with ethyl acetate (EtOAc) and evaporated to yield the EtOAc extract. All EtOAc extracts were evaluated for their antibacterial activity using agar diffusion method. RESULTS: The results indicated that the EtOAc extract from fungus RG-2 was the potential source of antibacterial compounds. Molecular identification showing fungus RG-2 was Xylaria sp. CONCLUSION: Further investigation of the antibacterial compounds produced by fungus Xylaria sp. derived from the flowers of A. paniculata will be performed in the future. To the best of our knowledge, endophytic fungal Xylaria sp. is firstly isolated from A. paniculata. © 2021 Suryelita Suryelita, Riga Riga, Sri Benti Etika, Mariam Ulfah, Muh Ade Artasasta.
Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, Padang, Indonesia; Department of Pharmacy, STIKES Muhammadiyah Cirebon, Cirebon, Indonesia; Department of Biotechnology, Faculty of Mathematics and Natural Sciences, University Negeri Malang, Malang, Indonesia
