S. Syamsurizal, D. Handayani, H. Kadri, E. Badriyya
The prevalence of T2DM is quite high in Indonesian Melayu ethnic. T2DM is a metabolic disorder that is difficult to cure but can be inhibited by its expression. T2DM expression inhibited by knowing its genetic markers. The strong genetic marker for T2DM and widely studied in other countries is SNP rs7903146 TCF7L2 gene. The aim of the research was to identify SNP rs7903146 in TCF7L2 gene as a genetic marker of T2DM in Indonesian Melayu ethnic. Identification of SNP rs7903146 TCF7L2 uses direct DNA sequencing methods and then bioinformatics analysis. SNP rs7903146 in TCF7L2 gene can be a genetic marker of T2DM in Indonesian Melayu ethnic. © 2019 IOP Publishing Ltd.
Biology Department, Faculty of Mathematics and Science, Universitas Negeri Padang, Jl. Prof. Dr. Hamka, Padang, West Sumatera, Indonesia; Faculty of Medicine, Universitas Andalas, Limau Manis, Sumatera Barat, Indonesia; Faculty of Pharmacy, Universitas Andalas, Limau Manis, Sumatera Barat, Indonesia