Alizar Ulianas, Nurlely, Yulkifli, Lee Yook Heng, Tan Ling Ling
A micro-sized poly(n-butyl acrylate-co-N-acryloxysuccinimide) [poly(nBA-co-NAS] copolymer bio-carrier matrix has been synthesized from n-butyl acrylate (nBA) and N-acryloxysuccinimide (NAS) monomers through a single step emulsion photopolymerization protocol. Narrower size distribution of the copolymer microspheres having a size in the range of 0.31-1.04 μm was obtained using nBA-SDS composition ratio of 0.25:5.00 (mL: mg). The FTIR analysis result confirmed the presence of the useful succinimide functional groups on the poly(nBA-co-NAS), which rendered the copolymer microspheres a feasible alternative to other polymers for use as biological immobilization carrier for enzymes and DNA molecules in the fabrication of advanced biosensor devices. The low glass transition temperature (Tg) of the as-synthesized copolymer microspheres signifies the soft and good adhesion properties of the matrix to be attached to the solid support to form the miniature solid-state biosensing devices. © International Journal on Advanced Science, Engineering and Information Technology.
Department of chemistry, Faculty of Mathematics and Science, Universitas Negeri Padang, Sumatera Barat, Indonesia; Department of Physic, Faculty of Mathematics and Science, Universitas Indonesia, Jakarta, Indonesia; Department of Physic, Faculty of Mathematics and Science, Universitas Negeri Padang, Sumatera Barat, Indonesia; School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, UKM, Bangi, Selangor D.E., 43600, Malaysia; Southeast Asia Disaster Prevention Research Initiative (SEADPRI-UKM), Institute for Environment and Development (LESTARI), Universiti Kebangsaan Malaysia, UKM, Bangi, Selangor, 43600, Malaysia
