Integrating Nanoparticles and Herbal Extracts with Platinum-Based Chemotherapy for Enhanced Efficacy and Reduced Toxicity (A Review)

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Palash Chandra Biswas, Vikash Jakhmola, Arnab Samanta, Anandi Kapri, Arif Nur Muhammad Ansori, Rahadian Zainul

2025 Pharmaceutical Chemistry Journal Vol. 59 Issue 2 Article Cited by 4 SDG 3SDG 17 Quartile

Abstract

Though various developments have occurred in the arena of cancer treatments, e.g. chemotherapy, these treatments have been associated with various adverse effects and the development of drug resistance. Thus, in this study, the effectiveness of the application of an integrated approach of nanoparticles and herbal extracts, along with platinum-based chemotherapy, is analyzed. Based on the reviewed studies in this manuscript, the findings of the existing studies have indicated the enhanced effectiveness of the aforementioned approach, which improves the potential use of phytochemicals to overcome the challenges associated with chemotherapy, along with improved anticancer effects. © Springer Science+Business Media, LLC, part of Springer Nature 2025.

Affiliations

Uttaranchal Institute of Pharmaceutical Sciences, Uttaranchal University, Dehradun, 248007, India; Netaji Subhas Chandra Bose Institute of Pharmacy, West Bengal, Chakdaha, 741222, India; Postgraduate School, Universitas, Airlangga, Surabaya, Indonesia; Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, Padang, Indonesia; Center for Advanced Material Processing, Artificial Intelligence and Biophysic Informatics (CAMPBIOTICS), Universitas Negeri Padang, Padang, Indonesia

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