Junian Cahyanto Wibawa, Nendra Febrianto, Muhammad Soleh Fudin, Yovhandra Ockta, Rifqi Festiawan
Study Purpose. This study aims to analyze the effect of physical exercise on increasing glutathione peroxidase as a biomarker for endogenous antioxidants. Materials and methods. This type of systematic review research uses searches from journal databases such as MEDLINE-Pubmed, Web of Science, Scopus and Science Direct. The inclusion criteria in this study were articles published in the last 5 years and articles discussing glutathione peroxidase, physical exercise and antioxidants. A total of 95 articles from the Science Direct, Pubmed, and Web of Science databases were identified. A total of 10 articles that met the inclusion criteria were selected and analyzed for this systematic review. For standard operations, this study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) assessment. Results. This systematic review reports that physical exercise has been shown to increase levels of glutathione peroxidase as a marker of endogenous antioxidants. Conclusions. Physical exercise has been proven to increase glutathione peroxidase levels as a marker of endogenous antioxidants. This increase is triggered by ROS which is a physiological response to exercise. © 2025 Federacion Espanola de Docentes de Educacion Fisica. All rights reserved.
STKIP PGRI Trenggalek, Indonesia; Universitas Negeri Padang, Indonesia; Universitas Jenderal Soedirman, Indonesia
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