Asmitha Bhateja, Pawan Kumar, Shilpa Gaidhane, Suhas Ballal, Sanjay Kumar, Mahakshit Bhat, Shilpa Sharma, M.Ravi Kumar, Sarvesh Rustagi, Mahalaqua Nazli Khatib, Nishant Rai, Sanjit Sah, Sorabh Lakhanpal, Ganesh Bushi, Muhammed Shabil, Khang Wen Goh, Prakasini Satapathy
Background: Road traffic accidents (RTAs) are a major global cause of mortality and morbidity, often resulting in psychological distress, including post-traumatic stress disorder (PTSD) among survivors. However, the lack of sufficient and comprehensive data on PTSD prevalence hinders the development of effective support strategies. This systematic review aimed to evaluate the frequency of PTSD among survivors of RTAs, highlighting the need for psychological support, follow-up care, and, when necessary, assessment for potential PTSD. Methods: Observational studies (such as Cross-sectional, Cohort, and Case-control) that reported frequency or prevalence of PTSD among RTA survivors were included. A comprehensive literature search was conducted in several bibliographic databases up to 10 September 2023. Nested Knowledge software facilitated screening, and the JBI tool was utilized for quality assessment. A random-effects model was applied in a meta-analysis using R software (version 4.2.2) to estimate pooled frequency. Results: Sixty-nine studies involving 16,977 participants across five continents were included. The pooled frequency of PTSD was 26 % (95 % CI: 22 % to 30 %), with notable heterogeneity (I2 = 96 %). Subgroup analysis highlighted geographical variations in frequencies. Sensitivity analysis confirmed the robustness of the findings, while funnel plot asymmetry and Egger's test suggested publication bias. Conclusion: There is a substantial variation of PTSD among RTA survivors worldwide, especially across different regions. This underscores the need for integrating psychological assessments and interventions into standard care for RTA survivors. © 2025
Centre of Research Impact and Outcome, Chitkara University, Punjab, Rajpura, 140417, India; Chitkara Centre for Research and Development, Chitkara University, Himachal Pradesh, 174103, India; One Health Centre, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education, Wardha, India; Department of Chemistry and Biochemistry, School of Sciences, JAIN (Deemed to be University), Karnataka, Bangalore, India; Department of Allied Healthcare and Sciences, Vivekananda Global University, Rajasthan, Jaipur, 303012, India; Department of Medicine, National Institute of Medical Sciences, NIMS University Rajasthan, Jaipur, India; Chandigarh Pharmacy College, Chandigarh Group of Colleges-Jhanjeri, Punjab, Mohali, 140307, India; Department of Chemistry, Raghu Engineering College, Andhra Pradesh, Visakhapatnam, 531162, India; School of Applied and Life Sciences, Uttaranchal University, Uttarakhand, Dehradun, India; Division of Evidence Synthesis, Global Consortium of Public Health and Research, Datta Meghe Institute of Higher Education, Wardha, India; Department of Biotechnology, Graphic Era (Deemed to be University), Clement Town Dehradun, 248002, India; Department of Allied Sciences, Graphic Era Hill University Clement Town Dehradun, 248002, India; Department of Paediatrics, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Maharashtra, Pune, 411018, India; Department of Public Health Dentistry, Dr. D.Y. Patil Dental College and Hospital, Dr. D.Y. Patil Vidyapeeth, Maharashtra, Pune, 411018, India; School of Pharmaceutical Sciences, Lovely Professional University, Phagwara, 144411, India; Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India; University of Cyberjaya, Persiaran Bestari, Cyber 11, 63000 Cyberjaya, Selangor Darul Ehsan, Malaysia; Noida Institute of Engineering and Technology (Pharmacy Institute), Greater Noida, India; University Medical Laboratories Techniques Department, AL-Mustaqbal University, Babil, Hillah, 51001, Iraq; Faculty of Data Science and Information Technology, INTI International University, Nilai, Malaysia; Faculty of Mathematics and Natural Sciences, Universitas Negeri Padang, Padang, Indonesia; Center for Research and Development, Chandigarh University, Punjab, Mohali, India
